I would prefer players to play characters of the same sex and race as yourselves, unless you have a strong preference to the contrary, as I get confused when the divergence is too great.
All PCs are members of the Loyalist faction of the Sabbat. Create them as per The Player's Guide to the Sabbat, with the following modifications:
The following clans are recommended: Tzimisce, Ventrue antitribu, Toreador antitribu.
The following clans are not available as PCs, for various in-game reasons: Lasombra, Tremere antitribu, Ravnos, Nosferatu antitribu.
I recommend making physical attributes your lowest priority, as you will seldom need them in-game. When you do need them, you may simply spend blood points to raise them.
Combat-related Abilities are not a priority in this setting; you should not place more than four points, total, in all such Abilities (a maximum of two is recommended).
All PCs must have some connection, however tenuous, with the entertainment industry. I would prefer all PCs to have strong ties to the city.
Humanity is just another path to the Loyalists; it may be bought up to 10. Keep in mind that, to a Loyalist, Humanity means they must regulate their own behaviour; it does not compel them to try to constrain others.
Degeneration rules will be rigidly enforced. Choose your path carefully; even ones that seem like "The Path of What You Wanted to Do Anyway" (eg. Path of Cathari), may require you to make difficult choices in this chronicle.
The Eat Food merit is so common among the Loyalists that many pick it up without meaning to; it may be taken at no cost. Seeing others eat generally does not disgust L.A. Loyalists the way it does other vampires.
I recommend the merit Common Sense, especially for experienced players. This version of the World of Darkness works a little differently from what you're used to, and Common Sense will allow retconning when you inevitably stumble over small differences in assumptions.
Each character starts with a Vinculum rating of one (or higher, by negotiation) towards all other Loyalists in Los Angeles.
Summarising your character's appearance as "He looks a little like X" is fine, especially if X is a celebrity and you can bring an appropriate picture of X along to sessions.
In addition to choosing your character's major motivation(s), decide what you want for your character, ie. how would you like their unlife to progress, how do you envision their story ending.
All set? Okay, then, altogether now:
Under the bridge downtown
Is where I drew some blood ...