Acne Vulgaris is a chronic, intermittent disease which may persist long past the teenage years; it is not unusual to find acne activity in the third and fourth decades of life.

Acne becomes rare in women after menopause but can persist into the sixth decade in some men.

Acne lesions are usually asymptomatic, although the nodules can be painful.

Occasionally, patients complain of itching in the acne lesions.

More darkly pigmented acne patients may be more bothered by the postinflammatory hyperpigmentation than by the acneiform lesions themselves.