In the western culture in which modern science and technology has arisen, we speak in daily life of reality and of the real as a domain of entities that exist independently from what we do as observers. Furthermore, we act and speak, both colloquially and technically, as if we knew we were able to make reference to such independent entities. The flow of normal daily life and experience, in which things appear to us as if they were there independently of what we do, seems to confirm this. Furthermore, the use that we make of the operational coherences of daily life for successful cognitive predictions of the consequences of our operations in it with objects also contributes to support this implicit view. This I want to change by reflecting further on the consequences of accepting the operational separation of the experience and explanation of the experience in the explanation of the biology of observing.